Product Name	Prescription Required?	Parasites	Safe For Other Pets	Side Effects	Water Resistance	Special Concerns	Minimum Age/Size	Active Ingredient
	Sentry Natural Defense	no	fleas and ticks	yes	skin irritation, hair loss,	yes; but can be removed with soap shortly after applications	very heavy clove scent; may have shorter duration than some other products	12 weeks	octopamine blocker
	Frontline Plus	no	fleas, ticks, lice	provided for cats as well, indicated safe for nursing and pregnant dogs		yes		8 weeks	fipronil and s-methoprene
	Advantage Multi	yes	flea, heartworms, whipworms, roundworms, hookworms	also available for cats, no information on prenant or nursing dogs	skin irritation, lethargy, loss of appetite, hyperactivity		medicinal odor, serious concerns if ingested including incoordination and tremors	7 weeks and 3 lbs	imidacloprid, moxidectin
	Bio Spot	no	fleas, ticks and mosquitos	lethal to cats and other animals	excessive salivation, seizures, muscle tremors, twitching, dilated pupils	bathing can dilute effectiveness, water resistant	not for use in young puppies, not to be combined with any other products	6 months	permethrin, s-methoprene IGR
	Sentinel	yes	fleas, heartworms, roundworms, hookworms, whipworms	safe for use in cats, pregnant and nursing dogs	depression, lethargy, vomiting, staggering, loss of appetite, diarrhea, seizures, weakness, excessive salivation		does not kill adult fleas, often used in combination with Capstar; beef flavor; must give with food; special caution for use in Collies and other herding breeds	4 weeks and 2 lbs	milbemycin oxime, lufenuron
	K9 Advantix	no	fleas, ticks, mosquitos	no		yes		7 weeks	imidacloprid, permethrin
	Revolution	yes	fleas, ticks, heartworms, ear mites, sarcoptic mange	yes, sold for cats as well, safe for pregnant and nursing dogs	loss of appetite, salivation, diarrhea, vomiting, tremors, fever, panting, skin irritation	yes (within 2 hours of application)	one spot application	6 weeks	selamectin
	Capstar	no	fleas	yes, sold for cats as well, safe for pregnant and nursing dogs		yes	not a preventative, safely dose as often as once a day; fast acting	4 weeks	nitepyram